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Although US 21 was once one of the major north-south routes, about half of it has been decommissioned. US 21 originally began in Cleveland, but now begins in Wytheville, Virginia at I-81 in the western part of the state. The route travels south, soon entering North Carolina, and after passing through Charlotte, enters South Carolina. US 21 passes through the state capital, Columbia, as it heads to the southern South Carolina coast near Beaufort.

We drove US 21 in 2000, and took these photographs while on that trip.

• Photos of US 21 in:
• Virginia
• North Carolina
• South Carolina
• View individual pictures of US 21 on Flickr.
• Learn about how the alignment of US 21 has changed since it was originally commissioned.

Other websites with photos and information about US 21:

• Information about the ends of US 21 can be found here on the www.usends.com website.

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